Development and quality evaluation of bioactive rich drink powder based on sea buckthorn

Abstract

Sea buckthorn berries have been used as an ancient medicine for thousands of years. Exceptional nutritional value and health benefits of sea buckthorn have been disclosed by recent research. Sea buckthorn berries are high in health-enhancing bioactive compounds. The major health benefits of sea buckthorn include anti-oxidation activities, anti-cancer properties, reduction of cardiovascular disease and improvement of immune system. Evidence suggests that diets rich in antioxidants reduce the risk of Alzheimer’s disease (AD) through direct effects on amyloid beta (Aβ, a hallmark of AD) and consequently influence AD pathogenesis. Despite the links between sea buckthorn and known AD risk factors (altered glucose metabolism and elevated cholesterol levels), the relationship between sea buckthorn and Aβ production/ degradation has not been fully characterised. The aim of this study was to develop a bioactive rich functional drink powder incorporating sea buckthorn and address this knowledge gap by administering drink powder and sea buckthorn to an inexpensive in vitro cell system and assess their effects on Aβ levels.